158876-70-1

Basic information

• Product Name: 2-(2-bromopyridin-4-yl)-1-(4-fluorophenyl)ethanone
• Synonyms: 2-(2-bromopyridin-4-yl)-1-(4-fluorophenyl)ethanone
• CAS NO: 158876-70-1
• Molecular Formula: C₁₃H₉BrFNO
• Molecular Weight: 294
• Mol File: 158876-70-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2-bromopyridin-4-yl)-1-(4-fluorophenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromopyridin-4-yl)-1-(4-fluorophenyl)ethanone(158876-70-1)
• EPA Substance Registry System: 2-(2-bromopyridin-4-yl)-1-(4-fluorophenyl)ethanone(158876-70-1)

Safety Data

• Hazardous Substances Data: 158876-70-1(Hazardous Substances Data)

Upstream product

• 4926-28-7 2-Bromo-4-picoline 
• 116332-54-8 4-fluoro-N-methoxy-N-methylbenzamide 
• 451-46-7 4-fluorobenzoic acid ethyl ester 

Downstream Products

• 581098-30-8 1-(2-bromopyridin-4-yl)-2-(4-fluorophenyl)ethane-1,2-dione 1-oxime 

Relevant articles and documents

THERAPEUTIC METHODS AND COMPOUNDS

The invention provides a compound of formula I: (I) or a pharmaceutically acceptable salt thereof, wherein R1-R5 Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful to treat malaria.

A concise and optimized four-step approach toward 2-(aryl-)alkylsulfanyl-, 4(5)-aryl-, 5(4)-heteroaryl-substituted imidazoles using alkyl- or arylalkyl thiocyanates

A convenient cyclization method leading to trisubstituted imidazoles in up to 84% yield is reported. Diverse 1-aryl-, 2-heteroaryl-substituted ethanones are converted into the corresponding α-oximino derivatives which are reduced under regioselective cond

Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes

A series of polysubstituted pyridin-4-yl imidazole inhibitors of p38 MAP (mitogen-activated protein) kinase was prepared as small molecular anticytokine agents and drug candidates for the treatment of chronic inflammatory diseases. The contribution of sub