158890-34-7 Usage
General Description
"Piperidine, 1-(chloroacetyl)-3,5-dimethyl- (9CI)" is a synthetic chemical compound that is part of the piperidine class. This chemical is known for its complex structure and is primarily used in the field of organic chemistry where it may serve as a reactant or intermediate in various chemical reactions. The presence of the chloroacetyl group indicates it may be used in the synthesis of other complex molecules. Specific information regarding its toxicological properties, physical or chemical characteristics, and safety handling are usually provided by manufacturers or standard chemical reference materials. Its precise application would depend largely on the objectives of the specific synthesis pathway or the particular organic chemistry research context.
Check Digit Verification of cas no
The CAS Registry Mumber 158890-34-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,8,8,9 and 0 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 158890-34:
(8*1)+(7*5)+(6*8)+(5*8)+(4*9)+(3*0)+(2*3)+(1*4)=177
177 % 10 = 7
So 158890-34-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H16ClNO/c1-7-3-8(2)6-11(5-7)9(12)4-10/h7-8H,3-6H2,1-2H3
158890-34-7Relevant articles and documents
Synthesis and anticancer potential of novel xanthone derivatives with 3,6-substituted chains
Liu, Chaomei,Zhang, Mei,Zhang, Zhenhuan,Zhang, Steven B.,Yang, Shanmin,Zhang, Amy,Yin, Liangjie,Swarts, Steven,Vidyasagar, Sadasivan,Zhang, Lurong,Okunieff, Paul
, p. 4263 - 4271 (2016/08/23)
In an effort to develop new drug candidates with enhanced anticancer activity, our team synthesized and assessed the cytotoxicity of a series of novel xanthone derivatives with two longer 3,6-disubstituted amine carbonyl methoxy side chains on either benzene ring in selected human cancer cell lines. An MTT assay revealed that a set of compounds with lower IC50values than the positive control, 5-FU, exhibited greater anticancer effects. The most potent derivative (XD8) exhibited anticancer activity in MDA-MB-231, PC-3, A549, AsPC-1, and HCT116 cells lines with IC50values of 8.06, 6.18, 4.59, 4.76, and 6.09?μM, respectively. Cell cycle analysis and apoptosis activation suggested that the mechanism of action of these derivatives includes cell cycle regulation and apoptosis induction.
