1588971-95-2

Upstream product

• 937-31-5 (4-Nitrophenyl)acetylene 
• 1588973-68-5 4-hydroxy-1-(2-iodophenyl)-4-methylpent-2-yn-1-one 
• 1588972-66-0 4-hydroxy-4-methyl-1-(2-((4-nitrophenyl)ethynyl)phenyl)pent-2-yn-1-one 

Relevant academic research and scientific papers

Facile synthesis of halogenated spiroketals via a tandem iodocyclization

A strategy for the synthesis of spiroketal compounds through a tandem iodocyclization of 1-(2-ethynylphenyl)-4-hydroxybut-2-yn-1-one derivatives is presented. This reaction could proceed under very mild conditions in a short time and avoid the use of expensive and toxic metal catalysts. Moreover, the resulting halides can be further exploited by subsequent palladium-catalyzed coupling reactions, which act as the important intermediates for building other valuable compounds.