1588972-07-9

Upstream product

• 1588972-77-3 4-butyl-4-hydroxy-1-(2-((4-methoxyphenyl)ethynyl)phenyl)oct-2-yn-1-one 
• 1588973-35-6 C₂₇H₃₂O₃ 
• 7737-41-9 dibutylethynylcarbinol 
• 176910-67-1 2-(4-methoxyphenylethynyl)benzaldehyde 
• 26260-02-6 2-iodobenzaldehyde 
• 768-60-5 4-methoxyphenylacetylen 

Relevant academic research and scientific papers

Facile synthesis of halogenated spiroketals via a tandem iodocyclization

A strategy for the synthesis of spiroketal compounds through a tandem iodocyclization of 1-(2-ethynylphenyl)-4-hydroxybut-2-yn-1-one derivatives is presented. This reaction could proceed under very mild conditions in a short time and avoid the use of expensive and toxic metal catalysts. Moreover, the resulting halides can be further exploited by subsequent palladium-catalyzed coupling reactions, which act as the important intermediates for building other valuable compounds.