1589574-10-6

Basic information

• Product Name: (4-bromophenyl)(1-methylindolizin-3-yl)methanone
• CAS NO: 1589574-10-6
• Molecular Weight: 314.181
• Mol File: 1589574-10-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-bromophenyl)(1-methylindolizin-3-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-bromophenyl)(1-methylindolizin-3-yl)methanone(1589574-10-6)
• EPA Substance Registry System: (4-bromophenyl)(1-methylindolizin-3-yl)methanone(1589574-10-6)

Safety Data

• Hazardous Substances Data: 1589574-10-6(Hazardous Substances Data)

Upstream product

• 6320-91-8 1-(2-(4-bromophenyl)-2-oxoethyl)pyridin-1-ium iodide 
• 123-38-6 propionaldehyde 

Relevant articles and documents

Iodine-promoted synthesis of 1-alkyl-3-aroylindolizines from N-(Aroylmethyl)pyridinium salts and aliphatic aldehydes

An effective and practical method has been developed for the diversity-oriented synthesis of 1-alkyl-3-aroylindolizines via the 1,3-dipolar cycloaddition of pyridinium ylides and aliphatic aldehydes in the presence of molecular iodine and a catalytic amount of MnO2. The synthesis proceeds by tandem reactions involving [3+2] cycloaddition, dehydration of the cycloadduct, and dehydroaromatization. Molecular iodine served both as a catalyst and a dehydroaromatization reagent in the reaction.