158959-43-4

Basic information

• Product Name: Benzene, 1-[4,4-dimethyl-2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-4-fluoro-
• CAS NO: 158959-43-4
• Molecular Formula: C20H21FO2S
• Molecular Weight: 344.45
• Mol File: 158959-43-4.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Benzene, 1-[4,4-dimethyl-2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-4-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-[4,4-dimethyl-2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-4-fluoro-(158959-43-4)
• EPA Substance Registry System: Benzene, 1-[4,4-dimethyl-2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-4-fluoro-(158959-43-4)

Safety Data

• Hazardous Substances Data: 158959-43-4(Hazardous Substances Data)

Upstream product

• 158959-77-4 1-[2-(4-fluorophenyl)-4,4-dimethylcyclopenten-1-yl]-4-(methylthio) benzene 
• 58518-77-7 ((1-(4-fluorophenyl)vinyl)oxy)trimethylsilane 
• 159429-78-4 1-(4-Fluoro-phenyl)-3,3-dimethyl-5-(4-methylsulfanyl-phenyl)-pentane-1,5-dione 
• 159429-74-0 Trimethyl-[1-(4-methylsulfanyl-phenyl)-vinyloxy]-silane 
• 1027313-67-2 3-Hydroxy-3-methyl-1-(4-methylsulfanyl-phenyl)-butan-1-one 
• 159429-75-1 3-Methyl-1-(4-methylsulfanyl-phenyl)-but-2-en-1-one 

Downstream Products

• 158959-56-9 4-[2-(4-fluorophenyl)-4,4-dimethylcyclopenten-1-yl]benzenesulfonamide 

Relevant articles and documents

METHOD OF USING CYCLOOXYGENASE-2 INHIBITORS IN THE TREATMENT AND PREVENTION OF NEOPLASIA

This invention relates to the use of cyclooxygenase-2 inhibitors or derivatives thereof in preventing and treating neoplasia. In particular, the invention describes the method of preventing and treating epithelial cell neoplasia in a subject, said method comprising treating the subject with a therapeutically-effective amount of a compound of Formula (I) wherein A, R and R are as described in the specification.

Use of a COX-2 inhibitor and a NK-1 receptor antagonist for treating inflammation

The present invention provides the use of a COX-2 inhibitior and an NK-1 receptor antagonist for the treatment or prevention of inflammatory disorders.

Combination therapy in the prevention of cardiovascular disorders

This invention relates to the use of cyclooxygenase-2 inhibitors or derivatives thereof in preventing cardiovascular disorders.