1589638-42-5

Basic information

• Product Name: 2-cyano-N-cyclopentyl-3-(2,4-dimethoxy-6-((E)-4-methoxystyryl)phenyl)acrylamide
• Synonyms: 2-cyano-N-cyclopentyl-3-(2,4-dimethoxy-6-((E)-4-methoxystyryl)phenyl)acrylamide
• CAS NO: 1589638-42-5
• Molecular Weight: 432.519
• Mol File: 1589638-42-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-cyano-N-cyclopentyl-3-(2,4-dimethoxy-6-((E)-4-methoxystyryl)phenyl)acrylamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyano-N-cyclopentyl-3-(2,4-dimethoxy-6-((E)-4-methoxystyryl)phenyl)acrylamide(1589638-42-5)
• EPA Substance Registry System: 2-cyano-N-cyclopentyl-3-(2,4-dimethoxy-6-((E)-4-methoxystyryl)phenyl)acrylamide(1589638-42-5)

Safety Data

• Hazardous Substances Data: 1589638-42-5(Hazardous Substances Data)

Upstream product

• 906457-43-0 (E)-2,4-dimethoxy-6-(4-methoxystyryl) benzaldehyde 
• 15112-75-1 2-cyano-N-cyclopentylacetamide 
• 1003-03-8 Cyclopentamine 

Relevant articles and documents

Synthesis of resveratrol acrylamides derivatives and biological evaluation of their anti-proliferative effect on cancer cell lines

A new series of resveratrol acrylamides amine derivatives was designed, synthesized, and evaluated for their anti-proliferative activity against three cancer cell lines including human chronic myelocytic leukemia cell K562, human hepatoma HuH-7 and human lung carcinoma A549. Most of the compounds showed superior activity against three cell lines when compared to parent resveratrol. C13 had the best anti-tumor activity against the HuH-7 cell line and its IC 50 was 4.5 μmol/L; C16 had the best anti-tumor activity against the K562 cell line and its IC50 was 2.9 μmol/L; C18 had the best anti-tumor activity against the A549 cell line and its IC50 was 3.8 μmol/L. It could be seen that the activity of the aromatic amine derivatives was better than the fatty amine derivatives by analyzing the experimental data.