158985-08-1 Usage
Uses
Used in Pharmaceutical Research and Development:
3-[[4-(4-Iodophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine is used as a chemical compound for the development of new therapeutic agents. Its unique structure and potential as a receptor ligand make it a valuable candidate for further research and drug development.
Used in Receptor Binding Studies:
In the field of medicinal chemistry, 3-[[4-(4-Iodophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine is used as a ligand for studying receptor binding and interactions. This helps researchers understand its potential pharmacological effects and mechanisms of action, which can contribute to the discovery of new drugs and therapies.
Used in Drug Design and Optimization:
3-[[4-(4-Iodophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine is utilized in the process of drug design and optimization. Its unique chemical features can be leveraged to modify and improve the properties of existing drugs or to design new molecules with enhanced therapeutic potential.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 3-[[4-(4-Iodophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine is used as a starting point for the synthesis of new compounds with potential therapeutic applications. Its structural features can be modified to explore various chemical and biological properties, leading to the development of novel drugs and pharmaceutical agents.
Check Digit Verification of cas no
The CAS Registry Mumber 158985-08-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,8,9,8 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 158985-08:
(8*1)+(7*5)+(6*8)+(5*9)+(4*8)+(3*5)+(2*0)+(1*8)=191
191 % 10 = 1
So 158985-08-1 is a valid CAS Registry Number.
158985-08-1Relevant academic research and scientific papers
Synthesis of 3-[[4-(4-[18F] fluorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine
Eskola, Olli,Bergman, Joergen,Lehikoinen, Pertti,Haaparanta, Merja,Groenroos, Tove,Forsback, Sarita,Solin, Olof
, p. 687 - 696 (2007/10/03)
3-[[4-(4-[18F]fluorophenyl)piperazin-1-yl]methyl] -1H-pyrrolo[2,3-b]pyridine, a candidate to image dopamine D4 receptors, was synthesised via electrophilic fluorination of a trimethylstannyl precursor with high specific radioactivity
Pyrrolo-pyridine derivatives
-
, (2008/06/13)
A class of pyrrolo[2,3-b]pyridine derivatives, substituted at the 3-position by a substituted piperazinylmethyl moiety, are antagonists of dopamine receptor subtypes within the brain, having a selective affinity for the dopamine D 4 receptor subtype over other dopamine receptor subtypes, and are accordingly of benefit in the treatment and/or prevention of psychotic disorders such as schizophrenia while manifesting fewer side-effects than those associated with classical neuroleptic drugs.
