159010-27-2Relevant academic research and scientific papers
New Thiol Inhibitors of Neutral Endopeptidase EC 3.4.24.11: Synthesis and Enzyme Active-Site Recognition
Gomez-Monterrey, Isabel,Beaumont, Ann,Nemecek, Patrick,Roques, Bernard P.,Fournie-Zaluski, Marie-Claude
, p. 1865 - 1873 (1994)
Selective, as well as mixed, inhibitors of the two zinc metallopeptidases, neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE), are of major clinical interest in the treatment of hypertension and cardiac failure.New thiol inhibitors, corre
