1590401-04-9Relevant academic research and scientific papers
Palladium-catalyzed glycosylation: Novel synthetic approach to diverse n -heterocyclic glycosides
Ji, Li,Xiang, Shao-Hua,Leng, Wei-Lin,Le Mai Hoang, Kim,Liu, Xue-Wei
supporting information, p. 1357 - 1360 (2015/03/30)
An efficient and highly stereoselective method for the construction of N-heterocyclic glycosides is reported. This method is based on a palladium-catalyzed allylation which proceeded to provide N-heterocyclic glycosyl compounds in good-to-excellent yields with β- or α-selectivity. Various N-nucleophiles were examined for this reaction and selected N-glycosyl isatin substrates were further elaborated to bis-indole sugars which have potential as antiproliferative drugs.
One-pot synthesis of β-N-glycosyl imidazole analogues via a palladium-catalysed decarboxylative allylation
Xiang, Shaohua,He, Jingxi,Ma, Jimei,Liu, Xue-Wei
supporting information, p. 4222 - 4224 (2014/04/17)
A concise and highly efficient strategy for the synthesis of N-glycosyl imidazole analogues is reported. This reaction is based on a palladium catalysed decarboxylative allylation and three steps, namely, carbamation, decarboxylation and allylation are involved. All the substrates can afford the desired products with excellent yields and selectivities. the Partner Organisations 2014.
