159054-14-5 Usage
Uses
Used in Organic Synthesis:
ETHYL 3-(2-CARBOXY-VINYL)-4,6-DICHLORO-1H-INDOLE-2-CARBOXYLATE is used as a substrate in organic synthesis for the creation of complex organic molecules. Its unique structure and reactivity allow for versatile chemical reactions, facilitating the synthesis of a wide range of compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, ETHYL 3-(2-CARBOXY-VINYL)-4,6-DICHLORO-1H-INDOLE-2-CARBOXYLATE serves as an intermediate in the production of various pharmaceutical products. Its potential applications in drug development are attributed to its structural properties, which can be leveraged to create novel therapeutic agents.
Used in Agrochemical Development:
ETHYL 3-(2-CARBOXY-VINYL)-4,6-DICHLORO-1H-INDOLE-2-CARBOXYLATE also has potential uses in the agrochemical sector. Its reactivity and structural features make it a candidate for the development of new agrochemicals, potentially contributing to advancements in crop protection and management.
Used in Materials Science:
In the field of materials science, ETHYL 3-(2-CARBOXY-VINYL)-4,6-DICHLORO-1H-INDOLE-2-CARBOXYLATE may be utilized as a building block for the synthesis of new materials with unique properties. Its chemical versatility can contribute to the development of innovative materials with applications in various industries.
Overall, ETHYL 3-(2-CARBOXY-VINYL)-4,6-DICHLORO-1H-INDOLE-2-CARBOXYLATE is a versatile chemical compound with a broad range of applications across different industries, including organic synthesis, pharmaceutical research, agrochemical development, and materials science. Its unique structural properties and reactivity make it a valuable asset in the development of new products and technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 159054-14-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,9,0,5 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 159054-14:
(8*1)+(7*5)+(6*9)+(5*0)+(4*5)+(3*4)+(2*1)+(1*4)=135
135 % 10 = 5
So 159054-14-5 is a valid CAS Registry Number.
159054-14-5Relevant academic research and scientific papers
Discovery of 3-Substituted 1H-Indole-2-carboxylic Acid Derivatives as a Novel Class of CysLT1 Selective Antagonists
Chen, Huayan,Yang, Hui,Wang, Zhilong,Xie, Xin,Nan, Fajun
, p. 335 - 339 (2016/03/25)
The indole derivative, 3-((E)-3-((3-((E)-2-(7-chloroquinolin-2yl)vinyl)phenyl)amino)-3-oxoprop-1-en-1-yl)-7-methoxy-1H-indole-2-carboxylic acid (17k), was identified as a novel and highly potent and selective CysLT1 antagonist with IC50 values of 0.0059 ± 0.0011 and 15 ± 4 μM for CysLT1 and CysLT2, respectively.
Cycloalkyl indole-2-carboxylates as useful tools for mapping the 'North- Eastern' region of the glycine binding site associated with the NMDA receptor
Micheli, Fabrizio,Di Fabio, Romano,Capelli, Anna M.,Cugola, Alfredo,Curcuruto, Ornella,Feriani, Aldo,Gastaldi, Paola,Gaviraghi, Giovanni,Marchioro, Carla,Orlandi, Alessandra,Pozzan, Alfonso,Quaglia, Anna M.,Reggiani, Angelo,Van Amsterdam, Frank
, p. 73 - 80 (2007/10/03)
A novel series of indole-2-carboxylate analogues of GV150526(1) in which the terminal phenyl ring belonging to the side chain present in the position C-3 has been replaced with a bridged cycloalkyl group was synthesized and evaluated for its pharmacologic
Substituted indole-2-carboxylates as in vivo potent antagonists acting as the strychnine-insensitive glycine binding site
Di Fabio, Romano,Capelli, Anna M.,Conti, Nadia,Cugola, Alfredo,Donati, Daniele,Feriani, Aldo,Gastaldi, Paola,Gaviraghi, Giovanni,Hewkin, Cheryl T.,Micheli, Fabrizio,Missio, Andrea,Mugnaini, Manolo,Pecunioso, Angelo,Quaglia, Anna M.,Ratti, Emiliangelo,Rossi, Luciana,Tedesco, Giovanna,Trist, David G.,Reggiani, Angelo
, p. 841 - 850 (2007/10/03)
A series of indole-2-carboxylates bearing suitable chains at the C-3 position of the indole nucleus was synthesized and evaluated in terms of in vitro affinity using [3H]glycine binding assay and in vivo potency by inhibition of convulsions ind
