159105-86-9Relevant articles and documents
The Synthesis of D,L p-Vinylphenylglycine by Amidoalkylation, and its Reactions.
Sheffer-Dee-Noor, Shani,Ben-Ishai, Dov
, p. 7009 - 7018 (2007/10/02)
Amidoalkylation of (2-chloroethyl)benzene or (2-bromoethyl)benzene with α-hydroxyhippuric acid and N-methoxycarbonyl α-hydroxyglycine, followed by dehydrohalogenation, affords N-protected p-vinylphenylglycines.Transformation of the vinyl group leads to N-methoxycarbonyl-p-phenylglycine, N-methoxycarbonyl-p-(epoxyethyl)phenylglycine, N-methoxycarbonyl-p-formylphenylglycine and N-methoxycarbonyl-p-carboxyphenylglycine.The deprotection of these compounds is described.