159117-13-2Relevant academic research and scientific papers
Optically active diethyl N-(p-toluenesulfonyl)-aziridine 2-phosphonates as chiral synthons for the synthesis of β-substituted α-amino phosphonates
Dolence, E. Kurt,Roylance, Jason B.
, p. 3307 - 3322 (2007/10/03)
A versatile approach for the synthesis of both protected enantiomers of aziridine 2-phosphonates for use as chiral synthons has been developed. The aziridines arise from either (R)- or (S)-phosphonoserine diethyl esters followed by N-tosylation, O-mesylat
Enantioselective synthesis of diverse α-amino phosphonate diesters
Smith III, Amos B.,Yager, Kraig M.,Taylor, Carol M.
, p. 10879 - 10888 (2007/10/03)
An efficient, versatile protocol for the synthesis of highly enantioenriched α-amino phosphonate diesters has been devised. Addition of lithium diethyl phosphite to chiral chelating imines 31a-j, prepared from a variety of aldehydes and the chiral auxilia
