159143-77-8 Usage
Chemical Properties
White Solid
Uses
Different sources of media describe the Uses of 159143-77-8 differently. You can refer to the following data:
1. (3S,5S)-Dihydroxy Simvastatin is a derivtive of Simvastatin (S485000). Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.
2. A metabolite of Simvastatin (S485000).
Check Digit Verification of cas no
The CAS Registry Mumber 159143-77-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,9,1,4 and 3 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 159143-77:
(8*1)+(7*5)+(6*9)+(5*1)+(4*4)+(3*3)+(2*7)+(1*7)=148
148 % 10 = 8
So 159143-77-8 is a valid CAS Registry Number.
159143-77-8Relevant articles and documents
EX VIVO METHODS FOR PREDICTING AND CONFIRMING IN VIVO METABOLISM OF PHARMACEUTICALLY ACTIVE COMPOUNDS
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Page/Page column 47; 48; 49, (2015/06/25)
Methods and compositions for the catalytic oxidation of pharmaceutically active compounds, and more particularly to ex vivo methods for predicting in vivo metabolism of pharmaceutically active compounds, including predicting in vivo interaction between two or more pharmaceutically active compounds.
