15917-45-0Relevant academic research and scientific papers
Antiestrogen Basicity-Activity Relationships: A Comparison of the Estrogen Receptor Binding and Antiuterotrophic Potencies of Several Analogues of (Z)-1,2-Diphenyl-1-phenyl>-1-butene (Tamoxifen, Nolvadex) Having Altered Basicit
Robertson, David W.,Katzenellenbogen, John A.,Hayes, James R.,Katzenellenbogen, Benita S.
, p. 167 - 171 (2007/10/02)
A series of N-substituted (Z)-1,2-diphenyl-1--1-butenes, analogues of the antiestrogen tamoxifen (Nolvadex), in which the side-chain basicity is varied over a wide range, has been prepared to probe the importance of basicity in ev
