1591916-41-4Relevant academic research and scientific papers
One-pot multi-step cascade protocols toward β-indolyl sulfoximidoyl amidesviaintermolecular trapping of an α-indolylpalladium complex by CO
Liu, Huahua,Wei, Li,Chen, Zhiyuan
, p. 3359 - 3369 (2021/05/03)
Various β-indolyl sulfoximidoyl amides were efficiently prepared fromortho-iodoanilines, propargyl bromides, 1 atm of CO, and substitutedNH-sulfoximines, through a palladium-catalyzed indole annulation/carbonyl insertion/C-N bond formation cascade. Mostly good to high yields of the products were obtained through this multi-step, one-pot reaction protocol under very gentle reaction conditions. The obtained β-indolyl sulfoximidoyl amides could be converted into biologically interesting sulfoximine analogues that contain a tryptamine moiety.
Asymmetric Domino Heck/Dearomatization Reaction of β-Naphthols to Construct Indole-Terpenoid Frameworks
Wang, Dong-Chao,Cheng, Peng-Peng,Yang, Ting-Ting,Wu, Pan-Pan,Qu, Gui-Rong,Guo, Hai-Ming
, p. 7865 - 7872 (2021/10/20)
A palladium-catalyzed enantioselective Heck cyclization/dearomatization cascade via capturing the cyclized Heck π-allylpalladium intermediate by β-naphthols is reported, which provides a new strategy for the construction of chiral indole-terpenoid framewo
An approach to cyclohepta[ b ]indoles through an allenamide (4 + 3) cycloaddition-grignard cyclization-chugaev elimination sequence
He, Shuzhong,Hsung, Richard P.,Presser, William R.,Ma, Zhi-Xiong,Haugen, Bryan J.
, p. 2180 - 2183 (2014/05/06)
A strategy for synthesizing highly functionalized cyclohepta[b]indoles through a concise (4 + 3) cycloaddition-cyclization-elimination sequence is described. The cycloaddition features nitrogen-stabilized oxyallyl cations derived from epoxidations of N-ar
