159210-76-1

Basic information

• Product Name: 6-{[(2,5-dimethoxyphenyl)amino]methyl}-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine
• Synonyms: pyrido[2,3-d]pyrimidine-2,4-diamine, 6-[[(2,5-dimethoxyphenyl)amino]methyl]-5-methyl-
• CAS NO: 159210-76-1
• Molecular Formula: C₁₇H₂₀N₆O₂
• Molecular Weight: 340.3797
• Mol File: 159210-76-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 636.1°C at 760 mmHg
• Flash Point: 338.5°C
• Density: 1.349g/cm³
• Vapor Pressure: 4.42E-16mmHg at 25°C
• Refractive Index: 1.715
• CAS DataBase Reference: 6-{[(2,5-dimethoxyphenyl)amino]methyl}-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-{[(2,5-dimethoxyphenyl)amino]methyl}-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine(159210-76-1)
• EPA Substance Registry System: 6-{[(2,5-dimethoxyphenyl)amino]methyl}-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine(159210-76-1)

Safety Data

• Hazardous Substances Data: 159210-76-1(Hazardous Substances Data)

Upstream product

• 101348-32-7 2,4-diamino-6-(bromomethyl)-5-methylpyrido<2,3-d>pyrimidine 
• 102-56-7 2,5-dimethoxyaniline 
• 101810-73-5 2,4-diamino-5-methylpyrido<2,3-d>pyrimidine-6-carbonitrile 

Relevant articles and documents

Antimycobacterial activities of 2,4-diamino-5-deazapteridine derivatives and effects on mycobacterial dihydrofolate reductase

Development of new antimycobacterial agents for Mycobacterium aviurn complex (MAC) infections is important particularly for persons coinfected with human immunodeficiency virus. The objectives of this study were to evaluate the in vitro activity of 2,4-di

6-Substituted 2,4-diamino-5-methylpyrido[2,3-d]pyrimidines as inhibitors of dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents

The synthesis and biological activity of 15 6-substituted 2,4-diamino-5- methylpyrido[2,3-d]-pyrimidines are reported. These compounds were synthesized in improved yields by modifications of procedures previously reported by us. Specifically, dimethoxyphe