159222-57-8

Basic information

• Product Name: 2-(2-AMINOPHENYL)-5-(4-(TERT-BUTYL)PHENYL)-1,3,4-OXADIAZOLE
• Synonyms: 2-(2-AMINOPHENYL)-5-(4-(TERT-BUTYL)PHENYL)-1,3,4-OXADIAZOLE;2-{5-[4-(tert-butyl)phenyl]-1,3,4-oxadiazol-2-yl}aniline;2-[5-(4-tert-Butyl-phenyl)-[1,3,4]oxadiazol-2-yl]-phenylamine
• CAS NO: 159222-57-8
• Molecular Formula: C₁₈H₁₉N₃O
• Molecular Weight: 293.36
• Mol File: 159222-57-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 457.0±55.0 °C(Predicted)
• Appearance: /
• Density: 1.136±0.06 g/cm3(Predicted)
• PKA: 0.36±0.10(Predicted)
• CAS DataBase Reference: 2-(2-AMINOPHENYL)-5-(4-(TERT-BUTYL)PHENYL)-1,3,4-OXADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-AMINOPHENYL)-5-(4-(TERT-BUTYL)PHENYL)-1,3,4-OXADIAZOLE(159222-57-8)
• EPA Substance Registry System: 2-(2-AMINOPHENYL)-5-(4-(TERT-BUTYL)PHENYL)-1,3,4-OXADIAZOLE(159222-57-8)

Safety Data

• Hazardous Substances Data: 159222-57-8(Hazardous Substances Data)

Upstream product

• 43100-38-5 4-tert-butylbenzoic acid hydrazide 
• 91-56-5 indole-2,3-dione 

Relevant articles and documents

Synthesis of 2,5-disubstituted 1,3,4-oxadiazoles by visible-light-mediated decarboxylation–cyclization of hydrazides and diketones

A visible-light-induced synthesis of 2,5-disubstituted 1,3,4-oxadiazoles from simple diketones and hydrazides with the assistant of the photocatalyst eosin Y catalyzed decarboxylation and cyclization under mild conditions has been discovered. The reaction tolerates a wide range of functional groups and gives a variety of valuable 1,3,4-oxadiazoles in moderate to good yields. Finally, a plausible reaction mechanism was proposed.