159257-88-2

Basic information

• Product Name: N-(2-pyridinyl)-2-naphthamide
• Synonyms: N-(2-pyridinyl)-2-naphthamide
• CAS NO: 159257-88-2
• Molecular Formula: C16H12N2O
• Molecular Weight: 248.27928
• Mol File: 159257-88-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(2-pyridinyl)-2-naphthamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-pyridinyl)-2-naphthamide(159257-88-2)
• EPA Substance Registry System: N-(2-pyridinyl)-2-naphthamide(159257-88-2)

Safety Data

• Hazardous Substances Data: 159257-88-2(Hazardous Substances Data)

Upstream product

• 38922-71-3 2‐(naphthalen‐2‐yl)imidazo[1,2‐a]pyridine 
• 504-29-0 2-aminopyridine 
• 66-99-9 β-naphthaldehyde 
• 93-08-3 methyl 2-naphthyl ketone 
• 904239-04-9 [1-Naphthalen-2-yl-meth-(E)-ylidene]-pyridin-2-yl-amine 
• 2949-26-0 2-ethynylnaphthalene 

Relevant articles and documents

Singlet oxygen mediated dual C-C and C-N bond cleavage in visible light

A tandem cleavage of carbon-carbon and carbon-nitrogen bonds in imidazo[1,2-a]pyridines and imidazo[1,2-a]quinolines is reported in the presence of eosin Y and visible light. The ring opening occurs under ambient conditions through singlet oxygen insertio

Microwave-assisted heteropolyanion-based ionic liquid promoted sustainable protocol to N-heteroaryl amides via N-directing dual catalyzed oxidative amidation of aldehydes

A sustainable procedure for the synthesis of N-heteroaryl amides directly from oxidative amidation of aldehydes catalyzed by heteropolyanion-based ionic liquids under microwave-promoted conditions has been reported. The transformation has proven to tolerate a wide range of aldehydes and amino heterocycles with different functional groups. Moderate to excellent yields, solvent-free media, operational simplicity and reusability of catalysts are the main highlights. Furthermore, the proposed N-directing dual-catalysis mechanistic pathway was briefly investigated in this report.

A one-pot copper catalyzed biomimetic route to n -heterocyclic amides from methyl ketones via oxidative c-c bond cleavage

A direct one-pot Cu-catalyzed biomimetic oxidation of methyl ketones to pharmaceutically important N-heterocyclic amides is reported. The scope of the method is broad, scalable, and mild, and the reaction is tolerant with various acid, base sensitive functionalities with multiple heteroatoms and aryl halides. The extensive mechanistic studies suggest that this reaction follows the Luciferin-Luciferase-like pathway.