159267-58-0

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 159267-55-7 p-nitrobenzyl 7β-t-butoxycarbonylamino-1-carba(1-dethia)-3-<2-(3,4-dihydroxyphenyl)thiazol-4-yl>-3-cephem-4-carboxylate 
• 138038-53-6 p-nitrobenzyl 7β-t-butoxycarbonylamino-1-carba(1-dethia)-3-(2-bromomethylcarbonyl)-3-cephem-4-carboxylate 
• 138038-52-5 p-nitrobenzyl 7β-t-butyloxycarbonylamino-1-carba(1-dethia)-3-(2-bromo-1,1-diethoxyethyl)-3-cephem-4-carboxylate 
• 138038-50-3 p-nitrobenzyl 7β-phenoxyacetylamido-1-carba(1-dethia)-3-(2-bromo-1,1-diethoxyethyl)-3-cephem-4-carboxylate 
• 138038-51-4 p-nitrobenzyl 7β-phenoxyacetyl-t-butyloxycarbonylamino-1-carba(1-dethia)-3-(2-bromo-1,1-diethoxyethyl)-3-cephem-4-carboxylate 
• 123289-24-7 p-nitrobenzyl 7β-phenoxyacetylamido-1-carba(1-dethia)-3-(1-ethoxy-ethen-1-yl)-3-cephem-4-carboxylate 
• 108493-71-6 p-nitrobenzyl (7S,6R)-7-(phenoxyacetamido)-3-{[(trifluoromethyl)sulfonyl]oxy}-1-carba-1-dethia-3-cephem-4-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 138038-30-9 allyl 7β-t-butoxycarbonylamino-1-carba(1-dethia)-3-<2-<3,4-di(t-butyldimethylsilyloxy)phenyl>thiazol-4-yl>-3-cephem-4-carboxylate 
• 159267-59-1 7β-t-butoxycarbonylamino-1-carba(1-dethia)-3-<2-<3,4-di(t-butyldimethylsilyloxy)phenyl>thiazol-4-yl>-3-cephem-4-carboxylic acid 

Relevant academic research and scientific papers

Synthesis and in vitro antibacterial activities of 3-thiazol-4-yl-1-carba-1-dethiacephalosporins

The synthesis and microbiological evaluation of a new series of 3-thiazol-4-yl-carba-1-dethiacephalosporins is described. Structure activity relationship was achieved by changing substitution at the 2-position of the thiazole moiety. The result was a mark