1592683-34-5

Basic information

• Product Name: C₂₄H₂₂BrNO₄
• Synonyms: C₂₄H₂₂BrNO₄
• CAS NO: 1592683-34-5
• Molecular Weight: 468.347
• Mol File: 1592683-34-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₂BrNO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₂BrNO₄(1592683-34-5)
• EPA Substance Registry System: C₂₄H₂₂BrNO₄(1592683-34-5)

Safety Data

• Hazardous Substances Data: 1592683-34-5(Hazardous Substances Data)

Upstream product

• 5470-14-4 (6-bromobenzo[1,3]dioxol-5-yl)acetic acid 
• 51179-05-6 2-(4-(benzyloxy)phenyl)ethanamine 

Downstream Products

• 1592683-36-7 C₂₄H₂₂BrNO₃ 
• 1610775-08-0 C₂₄H₂₀BrNO₃ 
• 1592683-38-9 C₂₇H₂₆BrNO₅ 
• 1592683-39-0 C₂₇H₂₅NO₅ 

Relevant articles and documents

Evaluation of structural effects on 5-HT2A receptor antagonism by aporphines: Identification of a new aporphine with 5-HT2A antagonist activity

A set of aporphine analogs related to nantenine was evaluated for antagonist activity at 5-HT2A and α1A adrenergic receptors. With regards to 5-HT2A receptor antagonism, a C2 allyl group is detrimental to activity. The chiral center of nantenine is not important for 5-HT2A antagonist activity, however the N6 nitrogen atom is a critical feature for 5-HT2A antagonism. Compound 12b was the most potent 5-HT2A aporphine antagonist identified in this study and has similar potency to previously identified aporphine antagonists 2 and 3. The ring A and N6 modifications examined were detrimental to α1A antagonism. A slight eutomeric preference for the R enantiomer of nantenine was observed in relation to α1A antagonism.