159275-17-9

Basic information

• Product Name: BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
• Synonyms: BENZYL 4-(BROMOMETHYL)PIPERIDINE-1-CARBOXYLATE;BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE;BUTTPARK 95\50-67;N-(BENZYLOXYCARBONYL)-4-(BROMOMETHYL)PIPERIDINE;Benzyl 4-(bromoethyl)tetrahydro-1(2H)-pyridinecarboxylate;4-(Bromomethyl)piperidine, N-CBZ protected;N-(Benzyloxycarbonyl)-4-(bromomethyl)piperidine, 98 %;1-CBZ-4-(BROMOMETHYL)PIPERIDINE
• CAS NO: 159275-17-9
• Molecular Formula: C₁₄H₁₈BrNO₂
• Molecular Weight: 312.2
• Product Categories: Halides;Heterocycles;Methyl Halides;Pyrans, Piperidines &Piperazines;Piperidine;API intermediates;Methyl Halides;Pyrans, Piperidines & Piperazines
• Mol File: 159275-17-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 68 °C
• Boiling Point: 403.369 °C at 760 mmHg
• Flash Point: 197.751 °C
• Appearance: /
• Density: 1.357 g/cm³
• Vapor Pressure: 1.02E-06mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE(159275-17-9)
• EPA Substance Registry System: BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE(159275-17-9)

Safety Data

• Hazard Codes: Xi,C
• Statements: 36/37/38-34
• Safety Statements: 26-36/37/39-45
• Hazardous Substances Data: 159275-17-9(Hazardous Substances Data)

Usage

General Description

BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE is a chemical compound with the molecular formula C15H18BrNO2. It is a derivative of tetrahydropyridine and is commonly used in organic synthesis as a reagent. BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE is known for its versatile application in the production of pharmaceuticals, agrochemicals, and other fine chemicals. It is often utilized as a building block in the synthesis of various biologically active compounds. Additionally, BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE is valued for its ability to introduce the bromomethyl group into organic molecules, making it an important intermediate in the creation of diverse chemical structures.

InChI:InChI=1/C14H18BrNO2/c15-10-12-6-8-16(9-7-12)14(17)18-11-13-4-2-1-3-5-13/h1-5,12H,6-11H2

Upstream product

• 122860-33-7 benzyl 4-(hydroxymethyl)piperidine-N-carboxylate 
• 558-13-4 carbon tetrabromide 
• 159275-16-8 1-(benzyloxycarbonyl)piperidin-4-ylmethyl methanesulfonate 
• 10314-98-4 1-benzyloxycarbonylpiperidine-4-carboxylic acid 

Downstream Products

• 566905-91-7 benzyl 4-{[bis(tert-butoxycarbonyl)amino]methyl}piperidine-N-carboxylate 
• 247132-98-5 benzyl 4-(2-tert-butoxycarbonyl-1,2,3,4-tetrahydroisoquinolin-7-yloxymethyl)piperidin-1-carboxylate 
• 247132-78-1 benzyl 4-[2-(N,N'-di-tert-butoxycarbonylamidin)-1,2,3,4-tetrahydroisoquinolin-7-yloxymethyl]piperidine-1-carboxylate 
• 247132-78-1 4-[2-(N,N'-Di-tert-butoxycarbonylamidino)-1,2,3,4-tetrahydroisoquinolin-7-yloxymethyl]piperidine-1-carboxylic acid benzyl ester 
• 1240494-92-1 benzyl 4-((5-(4-fluorophenylcarbamoyl)pyridin-2-ylthio)methyl)piperidine-1-carboxylate 
• 368866-15-3 (S)-3-(1-((benzyloxy)-carbonyl)piperidin-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid 
• 1204122-88-2 Benzyl 4-({3-[hydroxy(diphenyl)methyl]-1H-1,2,4-triazol-1-yl}methyl)piperidine-1-carboxylate 
• 566905-99-5 2-(4-{[bis(tert-butoxycarbonyl)amino]methyl}piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate 
• 854261-83-9 N,N'-di-tert-butoxycarbonyl-7-[1-(2-nitrophenylmethyl)piperidin-4-ylmethoxy]-1,2,3,4-tetrahydroisoquinolin-2-carboxamidine 

Relevant articles and documents

LMP7 INHIBITORS

The present disclosure provides compounds that are Large Multifunctional Protease 7 (LMP7) inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of LMP7. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

Amidine compounds

A compound of the formula [I] wherein R1, R2and R3are the same or different and each is hydrogen atom, wherein each symbol is as defined in the specification, a salt thereof or a prodrug thereof. The compound of the presen

Phosphonic acid derivatives

A phosphonic acid derivative which is useful for medically treating hyperlipemia, represented by the following general formula (I) or a pharmacologically acceptable salt thereof: STR1 Representative example of the compound according to the present invention is one represented by the following formula: STR2