159308-03-9 Usage
Uses
4,6-DiMethoxy-β-Methyl-3-phenoxy AMbrisentan is a related compound of Ambrisentan (A575860) used as endothelin receptor antagonist in treating cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 159308-03-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,9,3,0 and 8 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 159308-03:
(8*1)+(7*5)+(6*9)+(5*3)+(4*0)+(3*8)+(2*0)+(1*3)=139
139 % 10 = 9
So 159308-03-9 is a valid CAS Registry Number.
159308-03-9Relevant articles and documents
Carboxylic acid derivatives, their preparation and use in treating cancer
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, (2008/06/13)
This invention provides a method for treating cancer in an individual, wherein the cancer is a tumor in which endothelin is upregulated (e.g. tumors of the prostate, lung, liver, breast, brain, stomach, colon, endometrium, testicle, thyroid, pituatary, bladder, kidney, pancreas and meninges) by administering to the individual an effective amount of a compound of Formula I or Formula Ia, as describe herein.
