159309-66-7

Basic information

• Product Name: 3-Pyridinol,2-amino-6-chloro-(9CI)
• Synonyms: 3-Pyridinol,2-amino-6-chloro-(9CI);3-Pyridinol, 2-aMino-6-chloro-;2-aMino-6-chloro-3-hydroxypyridine;2-AMino-6-chloro-3-pyridinol;2-aMino-6-chloropyridin-3-ol
• CAS NO: 159309-66-7
• Molecular Formula: C5H5ClN2O
• Molecular Weight: 144.559
• Product Categories: PYRIDINE
• Mol File: 159309-66-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 421.0±45.0 °C(Predicted)
• Appearance: /
• Density: 1.516±0.06 g/cm3(Predicted)
• PKA: 4.72±0.23(Predicted)
• CAS DataBase Reference: 3-Pyridinol,2-amino-6-chloro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinol,2-amino-6-chloro-(9CI)(159309-66-7)
• EPA Substance Registry System: 3-Pyridinol,2-amino-6-chloro-(9CI)(159309-66-7)

Safety Data

• Hazardous Substances Data: 159309-66-7(Hazardous Substances Data)

Usage

General Description

3-Pyridinol,2-amino-6-chloro-(9CI) is a chemical compound with the molecular formula C5H5ClN2O. It is a derivative of pyridine and contains an amino group and a chlorine atom. 3-Pyridinol,2-amino-6-chloro-(9CI) is used in the synthesis of pharmaceuticals and agrochemicals, and it has also been studied for its potential applications in organic chemistry and medicinal chemistry. Its properties and reactivity make it a valuable building block for the production of various compounds with biological and industrial significance. Additionally, it is important to handle this compound with care, as it may have potential risks and hazards associated with its handling and use.

Upstream product

• 41288-96-4 6-chloropyridine-3-ol 
• 887471-39-8 6-chloro-2-nitropyridin-3-ol 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL)

The application relates to heterocyclic compounds of the general formula (I), compositions comprising such compounds, a process for preparing these compounds and their medical use. The compounds act as monoacylglycerol lipase (MAGL) inhibitors and are useful in the treatment of neuroinflammation, neurodegenerative diseases, pain, cancer or mental disorders.

SUBSTITUTED AZA COMPOUNDS AS IRAK-4 INHIBITORS

The present invention provides substituted aza compounds of formula (I) or (II) and pharmaceutically acceptable salts thereof, and their use to inhibit IRAK-4 and/or for the treatment of diseases or disorders induced by IRAK-4.

BICYCLIC HETEROCYCLYL DERIVATIVES AS IRAK4 INHIBITORS

The present invention provides bicyclic heterocyclyl kinase enzyme inhibitor compounds of formula (I), which are therapeutically useful as kinase inhibitors, particularly IRAK4 inhibitors. wherein A, Y, Z, X1, X2, X3, R1, R3, 'm', 'n' and 'p' have the meanings given in the specification and pharmaceutically acceptable salt or stereoisomer thereof that are useful in the treatment and prevention of diseases or disorder, in particular their use in diseases or disorder mediated by kinase enzyme, particularly IRAK4 enzyme. The present invention also provides pharmaceutical composition comprising at least one of the compounds of compound of formula (I) together with a pharmaceutically acceptable carrier, diluent or excipient therefor.