1593266-35-3Relevant academic research and scientific papers
Catalytic asymmetric bromoetherification and desymmetrization of olefinic 1,3-diols with C2-symmetric sulfides
Ke, Zhihai,Tan, Chong Kiat,Chen, Feng,Yeung, Ying-Yeung
, p. 5627 - 5630 (2014)
An enantioselective and highly diastereoselective bromoetherification and desymmetrization of olefinic 1,3-diols has been developed using a C 2-symmetric cyclic sulfide catalyst. This methodology has been successfully applied to the synthesis of the key intermediate of an orally active antifungal drug posaconazole (Noxafil).
