15936-10-4

Basic information

• Product Name: 2-CHLORO-1,8-NAPHTHYRIDINE
• Synonyms: 2-CHLORO-1,8-NAPHTHYRIDINE;1,8-Naphthyridine, 2-chloro-
• CAS NO: 15936-10-4
• Molecular Formula: C₈H₅ClN₂
• Molecular Weight: 164.59
• Mol File: 15936-10-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 138-139 °C
• Boiling Point: 281.489 °C at 760 mmHg
• Flash Point: 151.002 °C
• Appearance: /
• Density: 1.35 g/cm³
• Vapor Pressure: 0.006mmHg at 25°C
• Refractive Index: 1.663
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 2.04±0.30(Predicted)
• CAS DataBase Reference: 2-CHLORO-1,8-NAPHTHYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-1,8-NAPHTHYRIDINE(15936-10-4)
• EPA Substance Registry System: 2-CHLORO-1,8-NAPHTHYRIDINE(15936-10-4)

Safety Data

• Hazardous Substances Data: 15936-10-4(Hazardous Substances Data)

Usage

General Description

2-Chloro-1,8-naphthyridine is a chemical compound with the molecular formula C11H6ClN. It is a chlorinated naphthyridine derivative with potential pharmaceutical applications. 2-CHLORO-1,8-NAPHTHYRIDINE has been studied for its potential use in the treatment of bacterial and viral infections, as well as for its cytotoxic and anticancer properties. 2-Chloro-1,8-naphthyridine is a heterocyclic compound with a chlorine atom attached to the naphthyridine ring, and its unique structure makes it a promising candidate for the development of new drugs. Further research into the biological and pharmacological properties of 2-chloro-1,8-naphthyridine could lead to the development of novel therapeutic agents for a variety of diseases.

InChI:InChI=1/C8H5ClN2/c9-7-4-3-6-2-1-5-10-8(6)11-7/h1-5H

Upstream product

• 15936-09-1 2-hydroxy-1,8-naphthyridine 
• 1452560-14-3 (E)-methyl 3-(2-aminopyridin-3-yl)acrylate 
• 7521-41-7 2-Aminonicotinaldehyde 
• 15936-09-1 1,8-naphthyridine-2(1H)-one 

Downstream Products

• 960590-82-3 binaphthyridylamine 
• 15992-83-3 [1,8]naphthyridin-2-ylamine 
• 15936-09-1 2-hydroxy-1,8-naphthyridine 
• 87535-60-2 2-anilino-1,8-naphthyridine 
• 87535-62-4 2-cyclohexylamino-1,8-naphthyridine 
• 15936-02-4 2-phenyl-1,8-naphthyridine 

Relevant articles and documents

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HETEROBICYCLIC COMPOUNDS

Heterobicyclic compounds of Formula (I): or a pharmaceutically-acceptable salt, tautomer, or stereoisomer thereof, as defined in the specification, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, Huntington's Disease, and the like.

Pyridine and related aza heterocycle derivatives as cardiovascular agents

Novel pharmaceutical compounds and compositions having nitrogen containing ring systems which may be represented by the following structural formula: wherein R1 or R3 is a moiety of the formula: wherein R6 is selected from either hydrogen or acetyl; R7 is selected from 2, 3 or 4-pyridyl or 1-imidazolyl and Q is -(CH2)n, where n is an integer from 1 to 5 and R1 and R2, R2 and R3, R3 and R4 or R4 and R5 taken together may be -CH=CH-CH=CH-. The compounds and compositions are useful as inhibitors of thromboxane synthetase and in the treatment of hypertension and arrythmia in mammals.