159394-54-4

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 159394-55-5 1,3,4,5-tetrahydro-7,8-dimethoxy-5-methylpyrrolo<4,3,2-de>quinoline 
• 6315-89-5 3,4-dimethoxyaniline 
• 184957-78-6 4-(dimethoxymethyl)-6,7-dimethoxy-5-nitroquinoline 
• 159394-51-1 4-formyl-6,7-dimethoxy-5-nitroquinoline 
• 159394-50-0 6,7-dimethoxy-4-methyl-5-nitroquinoline 
• 105908-35-8 6,7-dimethoxy-4-methylquinoline 

Downstream Products

• 148613-96-1 1,3,4,5,7,8-hexahydro-5-methyl-1-(4-methylbenzenesulfonyl)pyrrolo<4,3,2-de>quinoline-7,8-dione 
• 138683-67-7 Damirone B 

Relevant academic research and scientific papers

Synthesis of Damirones A and B from a Quinoline

6,7-Dimethoxy-4-methylquinoline has been transformed in seven steps into the ortho-quinone, 1,3,4,5-tetrahydro-5-methyl-1-(4-methylphenylsulphonyl)-pyrroloquinoline-7,8-dione, 7 an intermediate which has previously been converted into the marine

Synthesis of pyrrolo[4,3,2-de]quinolines from 6,7-dimethoxy-4-methylquinoline. Formal total syntheses of damirones A and B, batzelline C, isobatzelline C, discorhabdin C, and makaluvamines A-D

2-Amino-4-nitrophenol and 2-methoxy-5-nitroaniline were converted into the 5-nitroquinolines 6b and 6d, respectively, and then the latter into nitro-acetal 6f. 6,7-Dimethoxy-4-methylquinoline (6g) was nitrated at C-5 and then the methyl substituent conver