1594127-49-7 Usage
Molecular Structure
1-Benzyl-6-oxo-1,6-dihydropyridine-3-boronic acid pinacol ester is a chemical compound with a pyridine ring structure, which is a six-membered aromatic ring with one nitrogen atom. It has a benzyl group attached to the 1-position and a boronic acid pinacol ester group at the 3-position. The compound also has an oxo group (C=O) at the 6-position.
Boronic Acid Pinacol Ester Derivative
The compound is a derivative of boronic acid pinacol ester, which is a valuable building block in organic synthesis. The pinacol ester group protects the boronic acid functionality, allowing it to be used in Suzuki-Miyaura cross-coupling reactions.
Suzuki-Miyaura Cross-Coupling Reactions
Boronic acid pinacol esters are known for their ability to undergo Suzuki-Miyaura cross-coupling reactions, which are widely used in the synthesis of carbon-carbon bonds. This makes them valuable building blocks in the synthesis of pharmaceuticals, agrochemicals, and materials.
Biological Activity
The compound is a dihydropyridine derivative, which is a class of compounds known for their potential biological activity. This makes it a useful intermediate for the preparation of various biologically active molecules.
Synthesis of Drug Candidates
Due to its potential biological activity and its ability to undergo Suzuki-Miyaura cross-coupling reactions, 1-Benzyl-6-oxo-1,6-dihydropyridine-3-boronic acid pinacol ester may be utilized in the development of novel drug candidates and other functionalized molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 1594127-49-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,9,4,1,2 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1594127-49:
(9*1)+(8*5)+(7*9)+(6*4)+(5*1)+(4*2)+(3*7)+(2*4)+(1*9)=187
187 % 10 = 7
So 1594127-49-7 is a valid CAS Registry Number.
1594127-49-7Relevant articles and documents
Iridium-Catalyzed β-C(sp2)?H Borylation of Enamides – Access to 3,3-Dihalogeno-2-methoxypiperidines
Gillaizeau, Isabelle,Dondasse, Isma?l,Nicolas, Cyril,Mimoun, Liliane,Sukach, Volodymyr,Meudal, Hervé
supporting information, (2022/02/07)
An efficient catalytic preparation of synthetically useful new β-borylated enamides was achieved under relatively mild conditions via a regioselective iridium-catalyzed C(sp2)?H borylation. The method features broad substrate scope, good functi
PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS
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Page/Page column 171; 172; 174, (2017/05/10)
Disclosed in the present application is a compound of formula (I) as defined herein as well as a pharmaceutical composition comprising said compound. Further disclosed in the present application is the use of such pharmaceutical compositions for treating diseases, namely inter alia for use in the treatment of cancer, metabolic, inflammatory, autoimmune and viral diseases. The compounds disclosed herein are inhibitors of MNK1 and/or MNK2 kinases.
INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES
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Page/Page column 137; 139, (2014/05/07)
Inhibitors of viral replication of formula (I), their process of preparation and their therapeutical uses. The present invention relates to compounds, their use in the treatment or the prevention of viral disorders, including HIV.
