159414-97-8 Usage
General Description
N4-Acetyl-2'-Fluoro-2'-deoxycytidine is a nucleoside analog with potential antineoplastic activity. This chemical is an acetylated fluoro-derivative of the nucleoside cytidine and is designed to inhibit DNA synthesis and repair. It potentially replaces cytidine in RNA during transcription and interferes with enzymes involved in DNA replication, leading to the inhibition of tumor cell growth. N4-Acetyl-2'-Fluoro-2'-deoxycytidine is being investigated for its potential use in the treatment of various types of cancer, including solid tumors and hematologic malignancies.
Check Digit Verification of cas no
The CAS Registry Mumber 159414-97-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,9,4,1 and 4 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 159414-97:
(8*1)+(7*5)+(6*9)+(5*4)+(4*1)+(3*4)+(2*9)+(1*7)=158
158 % 10 = 8
So 159414-97-8 is a valid CAS Registry Number.
159414-97-8Relevant articles and documents
NOVEL CHROMOPHORIC SILYL PROTECTING GROUPS AND THEIR USE IN THE CHEMICAL SYNTHESIS OF OLIGONUCLEOTIDES
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Page/Page column 30; 41, (2009/01/20)
The present invention provides compounds of the formula (I): C-Q-O-Si (R1)(R2)-N wherein C is a chromophore; Q is selected from the group consisting of optionally substituted aliphatic, aryl, heteroaryl, cycloalkyl or heterocycloalkyl; R1 and R2 are independently selected from the group consisting of optionally substituted C1-8 alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, C1-8 alkyloxy, cycloalkyloxy, heterocycloalkyloxy, alkylsilyloxy and arylsilyloxy; and N is a glycosylamine or abasic moiety.