159430-52-1

Basic information

• Product Name: 3(2H)-Pyridazinone,5-(1-piperazinyl)-(9CI)
• Synonyms: 3(2H)-Pyridazinone,5-(1-piperazinyl)-(9CI);5-PIPERAZIN-1-YLPYRIDAZIN-3(2H)-ONE
• CAS NO: 159430-52-1
• Molecular Formula: C8 H12 N4 O
• Molecular Weight: 180.21
• Product Categories: PIPERIDINE
• Mol File: 159430-52-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.42±0.1 g/cm3(Predicted)
• PKA: 11.22±0.40(Predicted)
• CAS DataBase Reference: 3(2H)-Pyridazinone,5-(1-piperazinyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Pyridazinone,5-(1-piperazinyl)-(9CI)(159430-52-1)
• EPA Substance Registry System: 3(2H)-Pyridazinone,5-(1-piperazinyl)-(9CI)(159430-52-1)

Safety Data

• Hazardous Substances Data: 159430-52-1(Hazardous Substances Data)

Upstream product

• 153276-34-7 4-chloro-5-(piperazin-1-yl)-2,3-dihydropyridazin-3-one 

Downstream Products

• 1421687-37-7 5-(4-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)pyridazin-3(2H)-one 
• 1421687-30-0 C₄₀H₄₃ClN₁₀O₄S₂ 
• 1421687-42-4 N-(7-(4-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)-4-fluoro-3-nitrobenzenesulfonamide 
• 1421687-51-5 tert-butyl (7-(4-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)((4-fluoro-3-nitrophenyl)sulfonyl)carbamate 
• 1421687-41-3 tert-butyl (7-(4-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)carbamate 
• 1421687-40-2 7-(4-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-amine 
• 1421687-39-9 5-(4-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-3-hydrazinylpyridazine 
• 1421687-38-8 3-chloro-5-(4-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)pyridazine 

Relevant articles and documents

The discovery of a selective, small molecule agonist for the mas-related gene X1 receptor

The novel 7-transmembrane receptor MrgX1 is located predominantly in the dorsal root ganglion and has consequently been implicated in the perception of pain. Here we describe the discovery and optimization of a small molecule agonist and initial docking s