159448-54-1Relevant academic research and scientific papers
AgONO-Assisted Direct C-H Arylation of Heteroarenes with Anilines
Gowrisankar, Saravanan,Seayad, Jayasree
supporting information, p. 12754 - 12758 (2015/03/30)
A novel copper-catalyzed C-H arylation of heteroarenes with anilines by an in situ diazonium reaction is established by using silver nitrite (AgONO) as an unconventional nitrosating reagent under acid-free conditions. It provides a complementary approach for the C-H arylation of electron-rich heteroarenes with aromatic amines affording a variety of heterobiaryls in moderate to good yields.
Synthesis of furans, pyrroles and pyridazines by a ruthenium-catalysed isomerisation of alkynediols and in situ cyclisation
Pridmore, Simon J.,Slatford, Paul A.,Taylor, James E.,Whittlesey, Michael K.,Williams, Jonathan M.J.
supporting information; experimental part, p. 8981 - 8986 (2009/12/27)
Alkyne-1,4-diols are readily available substrates which are isomerised to 1,4-diketones using Ru(PPh3)3(CO)H2/xantphos as a catalyst. In situ cyclisation into furans, pyrroles and pyridazines has been achieved under suitable conditions.
2,5-Disubstituted furans from 1,4-alkynediols
Pridmore, Simon J.,Slatford, Paul A.,Williams, Jonathan M.J.
, p. 5111 - 5114 (2008/02/09)
1,4-Alkynediols serve as readily available starting materials for isomerisation to 1,4-diketones, which can be converted in situ into the corresponding furans by acid-catalysed dehydration. A range of 2,5-disubstituted furans was prepared using the ruthenium-based catalyst Ru(PPh3)3(CO)H2 with Xantphos at 1 mol % loading.
Imidazole ethers having a II antagonist activity
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, (2008/06/13)
Compounds of general formula (I) STR1 wherein E is O or S; R is C 1 -C 5 straight, branched or cyclic alkyl or C 2 -C 5 alkenyl; X can be H, F, Cl, Br, I, CF 3 ; n is an integer 1 to 4; m is an integer 0 to 4; A and B are 5- or 6- membered aromatic carboc
Nonpeptide Angiotensin II Receptor Antagonists. Synthesis, in Vitro Activity, and Molecular Modeling Studies of N-imidazoles
Salimbeni, Aldo,Canevotti, Renato,Paleari, Fabio,Bonaccorsi, Fabrizio,Renzetti, Anna R.,et al.
, p. 3928 - 3938 (2007/10/02)
With the aim of explaining the influence of the structural changes on the biphenylic moiety on the activity, a series of N-imidazoles (I), constructed on the model of DuPont compounds by replacing either the central or terminal pheny
