159458-29-4

Basic information

• Product Name: 5-dodecyl-3-(phenylmethyl)isoxazole
• Synonyms: 5-dodecyl-3-(phenylmethyl)isoxazole
• CAS NO: 159458-29-4
• Molecular Weight: 327.51
• Mol File: 159458-29-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-dodecyl-3-(phenylmethyl)isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-dodecyl-3-(phenylmethyl)isoxazole(159458-29-4)
• EPA Substance Registry System: 5-dodecyl-3-(phenylmethyl)isoxazole(159458-29-4)

Safety Data

• Hazardous Substances Data: 159458-29-4(Hazardous Substances Data)

Upstream product

• 765-10-6 1-tetradecyne 
• 6125-24-2 2-Phenylnitroethane 
• 103-71-9 phenyl isocyanate 

Downstream Products

• 159458-30-7 (1)-5-dodecyl-α-phenyl-3-isoxazole acetic acid 
• 181863-45-6 (+/-)-3-Dodecyl-α-phenyl-5-isoxazole acetic acid 

Relevant articles and documents

Heterocyclic-substituted alkylamide acat inhibitors

Pharmaceutically useful compounds having ACAT inhibitory activity of the formula wherein n is 0, 1, or 2, for X other than tetrazole and n = 2 then R2 = R3 = H; R1 is phenyl, substituted phenyl, naphthyl, substituted naphthyl, a heteroaromatic group or a hydrocarbon group having from one to 18 carbon atoms; R2 and R3 are hydrogen, halo, hydroxy, alkyl, alkenyl, cycloalkyl, phenyl, substituted phenyl, a heteroaryl, or form a spiroalkyl group; x is a 5-membered heteromonocyclic group containing at least one to four heteroatoms selected from the group consisting of isothiazole, oxazole, thiazole, imidazole, furan, thiophene, pyrrole, tetrazole, 1,2,3-triazole, 1,2,4-oxadiazole, 1,3,4-oxadiazole, 1,3,4-thiadiazole, 1,2,4-triazole, and 1,2,4-oxadiazole said heteromonocyclic group being unsubstituted or substituted at any available position along the ring,

Isoxazolyl-substituted alkyl amide ACAT inhibitors

Pharmaceutically useful compounds having ACAT inhibitory activity of the formula STR1 wherein n is 0, 1, or 2, for X other than tetrazole and n=2 then R2 =R3 =H; R1 is phenyl, substituted phenyl, naphthyl, substituted naphthyl, a heteroaromatic group or a hydrocarbon group having from one to 18 carbon atoms; R2 and R3 are hydrogen, halo, hydroxy, alkyl, alkenyl, cycloalkyl, phenyl, substituted phenyl, a heteroaryl, or form a spiroalkyl group; X is a heteromonocyclic 5-membered ring containing one to four heteroatoms, said heteroatoms being nitrogen, oxygen or sulfur, and combination thereof; and R4 is a hydrocarbon group having from one to 20 carbon atoms are described as well as methods of their manufacture.