159465-27-7Relevant articles and documents
Tetrahydroisoquinoline compounds
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Paragraph 0412-0417, (2021/10/13)
The present invention provides a substituted aryl compound represented by the formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition and containing the same as PRMT5 inhibitor.
NEW ISOINDOLINE OR ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
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Page/Page column 31; 32, (2015/02/19)
Compounds of formula (I): (I) wherein Het, R3, R4, R5, R7, R8, R9, T, p, p', q, and q' are as defined in the description are pro-apoptotic agents useful in the treatment of cancers and of a
Syntheses of the marine metabolites verongamine, hemibastadin-2, and aerothionin using the cyano ylide coupling methodology
Wasserman, Harry H.,Wang, Jianji
, p. 5581 - 5586 (2007/10/03)
Syntheses of the marine metabolites verongamine, hemibastadin-2, and aerothionin have been accomplished by a methodology involving the conversion of a carboxylic acid to an acyl cyano phosphorane which may be oxidized to an α,β-diketo nitrile. This strong