159465-47-1Relevant articles and documents
Isothiocyanate-substituted benzyl ether opioid receptor ligands derived from 6β-naltrexol
Davis,Nelson
, p. 570 - 579 (1995)
A series of regioisomeric substituted 6-O-benzyl ethers of 6β-naltrexol (12) in which isothiocyanate groups were attached directly to or one carbon removed from the aromatic ring of the benzyl group were prepared. These agents were prepared to obtain elec
Synthesis and opioid receptor affinity of a series of aralkyl ethers of 6α- and 6β-naltrexol
Nelson,Davis,Nelson
, p. 4270 4277 (2007/10/02)
A series of 6-O-ethers of 6β- and 6α-naltrexol (6 and 7) were prepared to examine the effect of large aralkyl groups on affinity of the ligands for opioid receptors. The affinities of the 6β-and 6α-O-ether with benzyl, biphenylmethyl, 1- and 2-naphthylmet