15949-49-2

Basic information

• Product Name: 2-amino-5-chloro-N-phenylbenzamide
• CAS NO: 15949-49-2
• Molecular Formula: C₁₃H₁₁ClN₂O
• Molecular Weight: 246.6922
• Mol File: 15949-49-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 352.3°C at 760 mmHg
• Flash Point: 166.9°C
• Density: 1.351g/cm³
• Vapor Pressure: 3.87E-05mmHg at 25°C
• Refractive Index: 1.692
• CAS DataBase Reference: 2-amino-5-chloro-N-phenylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-5-chloro-N-phenylbenzamide(15949-49-2)
• EPA Substance Registry System: 2-amino-5-chloro-N-phenylbenzamide(15949-49-2)

Safety Data

• Hazardous Substances Data: 15949-49-2(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 635-21-2 5-chloroanthranilic acid 
• 108-86-1 bromobenzene 
• 5202-85-7 2-Amino-5-chlorobenzamide 
• 4743-17-3 5-Chloroisatoic anhydride 
• 2516-95-2 5-chloro-2-nitrobenzoic acid 
• 219487-62-4 5-chloro-2-nitro-N-phenylbenzamide 
• 41994-44-9 5-chloro-2-nitrobenzoyl chloride 

Downstream Products

• 7012-93-3 6-chloro-2,3-diphenylquinazolin-4(3H)-one 
• 92104-30-8 6-chloro-3-phenylquinazolin-4(3H)-one 
• 38511-69-2 6-chloro-2-methyl-3-phenyl-2,3-dihydro-1H-quinazolin-4-one 
• 4248-11-7 6-chloro-2-methyl-3-phenylquinazolin-4(3H)-one 

Relevant articles and documents

Visible-light-induced denitrogenative phosphorylation of benzotriazinones: A metal- And additive-free method for accessing: Ortho -phosphorylated benzamide derivatives

Metal-free, visible-light-induced denitrogenative phosphorylation of 1,2,3-benzotriazinones was achieved. With the use of eosin Y as a photoredox catalyst, N,N-diisopropylethylamine as a base, CH3CN-H2O as a solvent and sunlight or a blue LED as a light source, a variety of aryl-phosphonates, aryl-phosphinates, and aryl-phosphine oxides were efficiently prepared. In addition, B2pin2 instead of P-nucleophiles as a radical acceptor was also demonstrated. The key advantages of this newly developed method are the clean reaction profile, use of a low-cost organic-dye catalyst, energy efficiency, broad substrate scope, good to excellent yields and large-scale synthetic applicability. The gram-scale synthesised compounds could be isolated in pure form just upon extraction, followed by re-crystallisation; no tedious chromatographic purification was required.

Metal-free oxidative synthesis of quinazolinones via dual amination of sp3 C-H bonds

A novel metal-free synthesis of quinazolinones via dual amination of sp3 C-H bonds was developed. The sp3 carbon in methylarenes or adjacent to a heteroatom in DMSO, DMF or DMA was used as the one carbon synthon. This journal is the Partner Organisations 2014.

Some structural changes on triazolyl-benzotriazoles and triazolyl-benzimidazolones as potential potassium channel activators. III

This paper reports the synthesis and pharmacological evaluation of some compounds, obtained by structural modifications of 1,2,3-triazolyl-benzotriazoles and 1,2,3-triazolyl-benzimidazolones, which had shown activity as potential activators of the big-con