1595189-66-4Relevant articles and documents
Cyclic secondary sulfonamides: Unusually good inhibitors of cancer-related carbonic anhydrase enzymes
Moeker, Janina,Peat, Thomas S.,Bornaghi, Laurent F.,Vullo, Daniela,Supuran, Claudiu T.,Poulsen, Sally-Ann
, p. 3522 - 3531 (2014)
Carbonic anhydrase IX (CA IX) is a target for hypoxic cancer therapies, and the discovery of CA IX selective ligands is imperative for the development of these agents. Primary sulfonamides are broad specificity inhibitors of CA enzymes, while secondary su