1595283-07-0Relevant academic research and scientific papers
Bronsted acid-mediated reactions of aldehydes with 2-vinylaniline and biphenyl-2-amine
Zhang, Xu,Xu, Xuefeng,Yu, Lintao,Zhao, Qiang
, p. 2280 - 2282 (2014)
Herein we report simple Bronsted acid-mediated reactions of aldehydes with 2-vinylaniline and biphenyl-2-amine. Ultimately, the useful nitrogen-containing heterocycle derivatives are obtained. The electronic properties of the substituents on the aldehydes and 2-vinylaniline were investigated. It was found that molecules with both electron-donating and -withdrawing substituents were perfectly suitable substrates for this transformation, and the expected products were obtained in moderate to excellent yields.
Synthesis of Tetrahydroquinolines by Scandium-Catalyzed [3 + 3] Annulation of Anilines with Allenes and Dienes
Xu, Xian,Xu, Xin,Zheng, Xizhou
, p. 14995 - 15003 (2021/12/14)
This work reports a redox-neutral C–H/N–H annulation of anilines with allenes and dienes (1,3-dienes and 1,4-dienes) by using a scandium catalyst with a simple β-diketiminato ligand. In the reactions, both allene and diene coupling partners served as thre
Method for preparing 2-aryl-4-methyl quinoline compound
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Paragraph 0029; 0030; 0048; 0049; 0050; 0051, (2017/03/14)
The invention discloses a method for preparing a 2-aryl-4-methyl quinoline compound. The method comprises the following steps of: adding fluoride and an alkynyl imine compound into an organic solvent, and heating to react completely, wherein the structural formula of the alkynyl imine compound is as shown in the specification, and the structural formula of the 2-aryl-4-methyl quinoline compound is a shown in the specification, in the formulas, R1 is hydrogen, halogen, methyl, methoxyl, thiophene or cyanogen radical; R2 is hydrogen, methyl or methoxyl. Compared with the prior art, the 2-aryl-4-methyl quinoline compound can be prepared from one organism of the alkynyl imine compound under the action of the fluoride at one stime. The method disclosed by the invention is easy to operate and simple and convenient in aftertreatmnet, and the designability of substrates is good.
