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5-Chloro-3-methylpyrazole, a chemical compound with the molecular formula C4H5ClN2, is a pale yellow solid characterized by a molecular weight of 120.54 g/mol. It is widely recognized for its role as a building block in the synthesis of pharmaceuticals and agrochemicals, as well as for its ability to form coordination complexes with various metal ions, which makes it a valuable asset in catalytic and analytical chemistry. Additionally, it serves as a reagent in organic synthesis and a stabilizer in certain chemical reactions. However, due to its classification as a hazardous substance, it is crucial to handle 5-Chloro-3-methylpyrazole with caution to avoid skin and eye irritation.

15953-45-4

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15953-45-4 Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
5-Chloro-3-methylpyrazole is used as a key building block for the development of new pharmaceuticals and agrochemicals, contributing to the creation of innovative and effective products in these industries.
Used in Catalytic and Analytical Chemistry:
5-Chloro-3-methylpyrazole is utilized as a coordination complexing agent with various metal ions, playing a significant role in enhancing the efficiency and selectivity of catalytic processes and analytical techniques.
Used in Organic Synthesis:
As a reagent, 5-Chloro-3-methylpyrazole is employed in organic synthesis to facilitate specific chemical reactions, contributing to the formation of desired products with greater precision and yield.
Used as a Stabilizer in Chemical Reactions:
5-Chloro-3-methylpyrazole is used to stabilize certain chemical reactions, preventing unwanted side reactions and promoting the desired reaction pathways, thereby improving the overall efficiency and safety of the process.

Check Digit Verification of cas no

The CAS Registry Mumber 15953-45-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,9,5 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 15953-45:
(7*1)+(6*5)+(5*9)+(4*5)+(3*3)+(2*4)+(1*5)=124
124 % 10 = 4
So 15953-45-4 is a valid CAS Registry Number.
InChI:InChI=1/C4H5ClN2/c1-3-2-4(5)7-6-3/h2H,1H3,(H,6,7)

15953-45-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Chloro-3-methyl-1H-pyrazole

1.2 Other means of identification

Product number -
Other names 5-chloro-3-Methyl-1H-pyrazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15953-45-4 SDS

15953-45-4Relevant academic research and scientific papers

PYRROLO(PYRAZOLO)PYRIMIDINE DERIVATIVE AS LRRK2 INHIBITOR

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Paragraph 0157, (2020/11/23)

The present invention relates to a pyrrolo(pyrazolo)pyrimidine derivative having efficacy as an LRRK2 inhibitor, a preparation method therefor, and a pharmaceutical composition for preventing or treating degenerative brain diseases, containing the same.

3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1

Pelcman, Benjamin,Sanin, Andrei,Nilsson, Peter,No, Kiyo,Schaal, Wesley,?hrman, Sara,Krog-Jensen, Christian,Forsell, Pontus,Hallberg, Anders,Larhed, Mats,Boesen, Thomas,Kromann, Hasse,Vogensen, Stine Byskov,Groth, Thomas,Claesson, Hans-Erik

, p. 3024 - 3029 (2015/06/22)

Investigation of 1N-substituted pyrazole-3-carboxanilides as 15-lipoxygenase-1 (15-LOX-1) inhibitors demonstrated that the 1N-substituent was not essential for activity or selectivity. Additional halogen substituents on the pyrazole ring, however, increased activity. Further development led to triazole-4-carboxanilides and 2-(3-pyrazolyl) benzoxazoles, which are potent and selective 15-LOX-1 inhibitors.

PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION

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Page/Page column 46, (2008/12/08)

There is provided compounds of formula (I), wherein R1, R2, A1, A2, A3 and A4 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activit

PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION

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Page/Page column 50, (2008/06/13)

There is provided compounds of formula (I), wherein R1, R2, X1, X2 and n have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15-lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.

PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION

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Page/Page column 47-48, (2008/06/13)

There is provided compounds of formula (I), wherein R1, R2, X1, X2 and n have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15-lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.

PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION

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Page/Page column 41-42, (2010/10/20)

There is provided compounds of formula (I), wherein R1, R2, Ra and Rb have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15-lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.

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