159555-80-3Relevant academic research and scientific papers
Thermal rearrangement of nitrone and nitrile oxide cycloadducts to bicyclopropylidene. Synthesis of 3-spirocyclopropane-4-pyridone and furo[2,3-c]pyridine derivatives
Goti,Anichini,Brandi,Kozhushkov,Gratkowski,De Meijere
, p. 1665 - 1672 (1996)
Bicyclopropylidene smoothly undergoes 1,3-dipolar cycloadditions to nitrones or nitrile oxides under different reaction conditions. The strained bisspirocyclopropanated isoxazolidines obtained from nitrones easily rearrange upon heating with selective ope
Nitrone and Nitrile Oxide Cycloadditions to Bicyclopropylidene. Rearrangement of the Isoxazolidine Adducts to 3-Spirocyclopropane-4-pyridone Derivatives
Brandi, Alberto,Goti, Andrea,Kozhushkov, Sergei,Meijere, Armin de
, p. 2185 - 2186 (2007/10/02)
The two-step nitrone or nitrile oxide cycloaddition-rearrangement thermal process applied to bicyclopropylidene gives 4-pyridone, 7-indolizinone, and 2-quinolizinone derivatives containing a spirocyclopropane linkage α to a carbonyl group.
