159589-94-3Relevant academic research and scientific papers
Total synthesis of nortopsentins A-D, marine alkaloids
Kawasaki, Ikuo,Yamashita, Masayuki,Ohta, Shunsaku
, p. 1831 - 1839 (1996)
Nortopsentins A-D, antifungal 1,4-bisindolylimidazole marine alkaloids isolated from a sponge, were synthesized through palladium-catalyzed cross- coupling of 3-indolylboronic and 6-bromo-3-indolylboronic acids with halogenoimidazoles as the key reaction.
Successive Diarylation at the Carbon Positions (2/4 and 2/5) of 1H-Imidazole and its Application to the Total Synthesis of Nortopsentin D
Kaswasaki, Ikuo,Yamashita, Masayuki,Ohta, Shunsaku
, p. 2085 - 2086 (2007/10/02)
Nortopsentin D, an antifungal 2,4-diindolylimidazole, is synthesized by use of a successive and regioselective diarylation, in which N-protected 2,4,5-tri- and 4,5-di-bromoimidazole derivatives are treated with N-silylated 3-indolylboric acid in the prese
