159622-93-2

Basic information

• Product Name: (S)-(-)-2-(tert-Butyldiphenylsilyloxy)pentanal
• CAS NO: 159622-93-2
• Molecular Weight: 340.538
• Mol File: 159622-93-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-(-)-2-(tert-Butyldiphenylsilyloxy)pentanal(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-2-(tert-Butyldiphenylsilyloxy)pentanal(159622-93-2)
• EPA Substance Registry System: (S)-(-)-2-(tert-Butyldiphenylsilyloxy)pentanal(159622-93-2)

Safety Data

• Hazardous Substances Data: 159622-93-2(Hazardous Substances Data)

Downstream Products

• 161040-12-6 (Z)-(S)-6-(tert-Butyl-diphenyl-silanyloxy)-non-4-en-1-ol 
• 161040-09-1 (Z)-(S)-6-(tert-Butyl-diphenyl-silanyloxy)-non-4-enoic acid ethyl ester 

Relevant articles and documents

Diastereo- and enantioselective synthesis of 1,2-amino alcohols and protected α-hydroxy aldehydes from glycol aldehyde hydrazones

Starting from chiral glycol aldehyde hydrazones (S)-2, we prepared differently protected α-hydroxy aldehydes (R)- or (S)-4 as well as N-acetyl-protected 1,2-amino alcohols (R)-11 in high enantiomeric excesses via azaenolate α-alkylation or nucleophilic 1,2-addition to the CN double bond. The successive introduction of two vicinal stereogenic centres opens a new, flexible syn-diastereo- and enantioselective route to functionalised, N-acetyl-protected, vicinal amino alcohols (R,R)-13, which was demonstrated in the case of the γ-amino-β-hydroxycarboxylic acid statin (R,R)-15 and its analogues B. VCH Verlagsgesellschaft mbH, 1996.