1596351-16-4Relevant articles and documents
Stereoselective access to trisubstituted cyclopentanols from chiral unsaturated oxo esters by ketyl radical cyclization
Feuillastre, Sophie,Pelotier, Beatrice,Piva, Olivier
, p. 1753 - 1759 (2014/03/21)
Substituted cyclopentanols with three contiguous stereocenters were prepared with impressive diastereocontrol through a samarium diiodide induced 5-exo-trig radical process. The chiral unsaturated oxo ester precursors were prepared with ee values up to 90 % from propionaldehyde through a two-step organocatalyzed aldolization and Wittig-Horner olefination reaction sequence. Copyright
