15965-55-6

Usage

Structure

A benzimidazole derivative with a chlorine atom at the 2 position and a nitro group at the 4 position

Usage

Commonly used in organic synthesis and pharmaceutical research for the development of new drugs and bioactive compounds

Biological activity

Has been identified as a potential inhibitor for various enzymes and proteins, and has shown promising anti-cancer and anti-microbial properties in preliminary studies

Note

Further research is needed to fully understand its potential applications and biological effects.

Upstream product

• 85330-50-3 4-nitro-1H-benzo[d]imidazole-2(3H)-one 
• 3694-52-8 2,3-diamino-nitrobenzene 

Downstream Products

• 85330-50-3 4-nitro-1H-benzo[d]imidazole-2(3H)-one 
• 1378078-31-9 2-chloro-1H-1,3-benzodiazol-4-amine 
• 1446770-50-8 N-[2-({1-[3-(trifluoromethyl)phenyl]ethyl}amino)-1H-benzimidazol-4-yl]acetamide 

Relevant academic research and scientific papers

BENZIMIDAZOLYL-ACETAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS

This invention relates to novel benzimidazolyl-acetamide derivatives to formula (l) and their use as modulators of small-conductance calcium-activated potassium channels (SK channels). Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels.

TRICYCLIC INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION

This invention relates to tricycle I and its therapeutic and prophylactic uses, wherein the variables C1, C2, Z1, Z2, Q, J, R1, and R3 are defined in the specification. Disorders treated and/or prevented include rheumatoid arthritis.

CONFORMATIONALLY RESTRICTED AROMATIC INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD

Novel compounds are provided which are inhibitors of MTP and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases, and have the structure (I) or (IA) or (IB) including pharmaceutically acceptable salts thereof or prodrug esters thereof, wherein q is 0,1 or 2; R is H, alkyl, aryl or halogen; A is (1) a bond; (2) -O-; or (3) (i); B is: (ii) or (iii) or (iv) or (v) (wherein (a = 2, 3 or 4)) or (vi) or (vii) or (viii); and wherein L, L, R, R, R, R, R, R, R, R, R, X, (ix), (x) and (xi) are as defined herein.