1596803-18-7

Basic information

• Product Name: ethyl 4-{4-[3-(tert-butylthio)-2,5-dioxopyrrolidin-1-yl]-4,5,6,7,8,9-hexahydro-1H-cycloocta[d][1,2,3]triazol-1-yl}benzoate
• CAS NO: 1596803-18-7
• Molecular Weight: 484.619
• Mol File: 1596803-18-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 4-{4-[3-(tert-butylthio)-2,5-dioxopyrrolidin-1-yl]-4,5,6,7,8,9-hexahydro-1H-cycloocta[d][1,2,3]triazol-1-yl}benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-{4-[3-(tert-butylthio)-2,5-dioxopyrrolidin-1-yl]-4,5,6,7,8,9-hexahydro-1H-cycloocta[d][1,2,3]triazol-1-yl}benzoate(1596803-18-7)
• EPA Substance Registry System: ethyl 4-{4-[3-(tert-butylthio)-2,5-dioxopyrrolidin-1-yl]-4,5,6,7,8,9-hexahydro-1H-cycloocta[d][1,2,3]triazol-1-yl}benzoate(1596803-18-7)

Safety Data

• Hazardous Substances Data: 1596803-18-7(Hazardous Substances Data)

Upstream product

• 1596803-17-6 ethyl 4-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,5,6,7,8,9-hexahydro-1H-cycloocta[d][1,2,3]triazol-1-yl]benzoate 
• 75-66-1 2-methylpropan-2-thiol 
• 34899-59-7 (E)-1,8-dibromocyclooct-1-ene 
• 29916-92-5 cyclooct-2-yn-1-ol 
• 1596803-13-2 1-(cyclooct-2-yn-1-yl)-1H-pyrrole-2,5-dione 
• 38556-93-3 4-azido-benzoic acid ethyl ester 
• 7422-06-2 (Z)-3-bromocyclooct-1-ene 

Relevant articles and documents

A Route to Cyclooct-2-ynol and Its Functionalization by Mitsunobu Chemistry

A new silver-free synthesis for cyclooctynol is introduced. The obtained alcohol was further functionalized by a Mitsunobu reaction to give an assortment of imide and phenol derivatives. It was also possible to further functionalize the cyclooctyne by treatment with a fluorescein dye. As an interesting application, we used a cyclooctyne-maleimide conjugate as an azide-thiol crosslinker. A new synthesis for cyclooct-2-ynol is presented that does not employ silver salts. The obtained alcohol was further functionalized by Mitsunobu chemistry to afford new cyclooctynes.