159681-66-0Relevant academic research and scientific papers
ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS
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Page/Page column 133-134, (2021/05/21)
The disclosure relates to anti-cancer compounds which are anti-cancer PARP inhibitors of formula Al, A2, A3 or A4 conjugated by a linker to a steroid, whereby the steroid targets the conjugate to the nucleus, as well as to methods for their preparation and use. (I)
Acetic acid Wu Li Tuo raw material medicine impurity and preparation method and application thereof to standard product
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Paragraph 0017; 0018, (2016/11/28)
The invention relates to a new impurity generated in an acetic acid Wu Li Tuo synthesis process and a preparation method and application of the impurity. The impurity is 17 alpha-acetoxyl group-11 alpha-(4-N- methyl-N-formyl group phenyl group) 19-nor-pre
Synthesis of N-desmethyl derivatives of 17α-acetoxy-11β(4-N,N- dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione and mifepristone: Substrates for the synthesis of radioligands
Rao, Pemmaraju N.,Acosta, C. Kirk,Cessac, James W.,Bahr, Martin L.,Kim, Hyun K.
, p. 205 - 212 (2007/10/03)
The syntheses of N-desmethyl derivatives of CDB-2914 and the mono-N- desmethyl derivative of Mifepristone are described. We also describe the use of the mono-desmethyl derivatives as substrates for the synthesis of N- tritomethyl derivatives of CDB-2914 a
Oxidative Demethylation of 4-Substituted N,N-Dimethylanilines with Iodine and Calcium Oxide in the Presence of Methanol
Acosta, Kirk,Cessac, James W.,Rao, P. Narasimha,Kim, Hyun K.
, p. 1985 - 1986 (2007/10/02)
Reaction of para-substituted N,N-dimethylarylamines with iodine-calcium oxide in tetrahydrofuran-methanol affords N-methylarylamines in good yield.
