15971-96-7

Usage

InChI:InChI=1/C11H18O3/c12-10(7-4-8-11(13)14)9-5-2-1-3-6-9/h9H,1-8H2,(H,13,14)

Upstream product

• 872291-40-2 5-cyclohex-1-enyl-5-oxo-valeric acid 
• 16076-61-2 ethyl 5-cyclohexyl-5-oxopentanoate 
• 126389-93-3 2-hydroxy-[1,1'-bi(cyclohexan)]-1-en-3-one 
• 91765-15-0 5-cyclohex-1-enyl-5-oxo-valeric acid methyl ester 
• 144979-12-4 methyl 5-cyclohexyl-5-oxopentanoate 
• 1501-26-4 methyl 4-(chlorocarbonyl)butyrate 
• 1501-27-5 Pentanedioic acid, monomethyl ester 

Downstream Products

• 1015443-77-2 5-cyclohexyl-hex-5-enoic acid 
• 144979-12-4 methyl 5-cyclohexyl-5-oxopentanoate 

Relevant academic research and scientific papers

Enantioselective synthesis of Indolizidines bearing quaternary substituted stereocenters via rhodium-catalyzed [2 + 2 + 2] cycloaddition of alkenyl Isocyanates and terminal alkynes

An enantioselective synthesis of Indolizidines bearing quaternary substituted stereocenters by way of a rhodium-catalyzed [2 + 2 + 2] cycloaddition of substituted alkenyl Isocyanates and terminal alkynes Is described. The reaction provides lactam products using aliphatic alkynes, whereas aryl alkynes give rise to vlnylogous amide products. Through modification of the phosphoramldlte llgand, high levels of enantloselectlvlty, regloselectlvlty, and product selectivity are obtained for both products.

Biotransformation of cycloalkanediones by Caragana chamlagu

The biotransformation of alkylcycloalkanediones using suspension plant cultured-cells of Caragana chamlagu gave oxo carboxylic acids by oxidative cleavage. 5,6-Dioxoheptanoic acid was obtained in high yield (95%) in a short time (7 h) from 2-methyl-1,3-cyclohexanedione. However, 1,2- and 1,4-cycloalkanediones were reduced stereoselectively and trans-1,2-cyclohexanediol and trans-1,4-cyclohexanediol were obtained, respectively. The mechanism of the oxidative cleavage of alkylcycloalkanediones is also discussed.

Oxidative cleavage of the C-C bond of 3,6-dialkylcyclohexane-1,2-diones by cell suspension cultures of Marchantia polymorpha

Biotransformation of 3,6-dialkylcyclohexane-1,2-diones by cell suspension cultures of Marchantia polymorpha involves regio-selective oxidative cleavage of the C-C bond to give the corresponding oxocarboxylic acids shortened by one carbon unit. In the case of cyclohexane-1,2-dione, adipic acid was obtained.