159720-65-7Relevant academic research and scientific papers
Peptide Bond Formation via an Intramolecular Rearrangement
Wijkmans, Jac C. H. M.,Boom, Jacques H. van,Bloemhoff, Wim
, p. 7123 - 7126 (2007/10/02)
Intramolecular peptide synthesis could be achieved using tetrahydrophthalazine (1) as template.Peptide bond formation proceeded via the N-acyl-N'-α-aminoacylhydrazine-rearrangement.The feasibility of the approach is illustrated by the synthesis of the pro
