159727-81-8Relevant academic research and scientific papers
Therapeutic phenoxyalklpyridazines and intermediates therefor
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, (2008/06/13)
Compounds of the formula STR1 wherein: R1 and R2 are independently hydrogen, halo, alkyl, alkenyl, alkoxy, hydroxy, hydroxyalkyl, hydroxyhaloalkyl, alkoxyalkyl, alkylthioalkynyl, hydroxyalkoxy, alkylthioalkyl, alkylsulfinylalkyl, alk
An Evaluation of the Antirhinoviral Activity of Acylfuran Replacements for 3- Methylisoxazoles. Are 2-Acetylfurans Bioisosteres for 3-Methylisoxazoles?
Bailey, Thomas R.,Diana, Guy D.,Mallamo, John P.,Vescio, Niranjan,Draper, Tandy L.,et al.
, p. 4177 - 4184 (2007/10/02)
As a probe of the 3-methylisoxazole portion of our broad-spectrum antipicornaviral series, a panel of 2-acetylfuran analogues was prepared as replacements for the 3-methylisoxazole ring.Comparison of the two series showed remarkable similarity in potency,
