15974-34-2

Upstream product

• 13963-60-5 tris(N,N-diethyldithiocarbamato)cobalt(III) 
• 148-18-5 sodium N,N-diethyldithiocarbamate 
• 20624-25-3 sodium diethyldithiocarbamate trihydrate 
• 97-77-8 disulfiram 
• 7440-48-4 cobalt 

Relevant academic research and scientific papers

Cytotoxicity, anti-microbial studies of M(II)-dithiocarbamate complexes, and molecular docking study against SARS COV2 RNA-dependent RNA polymerase

Ten transition metal dithiocarbamate (DTC)complexes of the type [M(κ2-Et2DT)2] (1–5), and [M(κ2-PyDT)2] (6–10) (where M?=?Co, Ni, Cu, Pd, and Pt; Et2DT?=?diethyl dithiocarbamate; PyDT?=?pyrrolidine dithiocarbamate) were synthesized and characterized by different methods. The dithiocarbamate acted as bidentate chelating ligands to afford a tetrahedral complexes with Co(II) ion and square planner with other transition metal ions. The dithiocarbamate complexes showed good activity against the pathogen bacteria species. The results showed the Pt-dithiocarbamate complexes are more active against all the tested bacteria than the Pd-dithiocarbamate complex. The dithiocarbamate complexes displayed the maximum inhibition zone against E. coli bacteria, whereas the lowest activity of the dithiocarbamate against Salmonella typhimurium bacteria. The cytotoxicity of the Pd(II) and Pt(II) complexes was screened against the MCF-7 breast cancer cell line and the complexes showed moderate activity compared with the cis-platin. The results indicated that the MCF7 cells treated with 500?μgml of ligands and Pd(II) and Pt(II) complexes after 24 hr exposure showed intercellular space and dead cells. Finally, molecular docking studies were carried out to examine the binding mode of the synthesized compounds against the proposed target; SARS COV2 RNA-dependent RNA polymerase.

Effective optical faraday rotations of semiconductor EuS nanocrystals with paramagnetic transition-metal ions

Novel EuS nanocrystals containing paramagnetic Mn(II), Co(II), or Fe(II) ions have been reported as advanced semiconductor materials with effective optical rotation under a magnetic field, Faraday rotation. EuS nanocrystals with transition-metal ions, EuS:M nanocrystals, were prepared by the reduction of the Eu(III) dithiocarbamate complex tetraphenylphosphonium tetrakis(diethyldithiocarbamate)europium(III) with transition-metal complexes at 300 C. The EuS:M nanocrystals thus prepared were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), inductively coupled plasma atomic emission spectroanalysis (ICP-AES), and a superconducting quantum interference device (SQUID) magnetometer. Enhanced Faraday rotations of the EuS:M nanocrystals were observed around 550 nm, and their enhanced spin polarization was estimated using electron paramagnetic resonance (EPR) measurements. In this report, the magneto-optical relationship between the Faraday rotation efficiency and spin polarization is discussed.

An experimental and theoretical approach of spectroscopic and structural properties of the bis(diethyldithiocarbamate)-cobalt(II)

Theoretical and experimental bands have been assigned for the Fourier Transform Infrared spectrum (FT-IR) and FT-Raman of the bis(diethydithiocarbamate)Co(II) complex, [Co(DDTC)2]. The calculations have been based on the DFT/B3LYP method, second derivative spectrum and band deconvolution analysis. The UV-Vis experimental spectra of [Co(DDTC)2] was measured in the solid state and in an acetonitrile solution. The calculated electronic spectrum was estimated using the TD/PBE1PBE and TD/B3LYP methods 6-311G (d,p) basis set for all atoms. The Bond Orbital Analysis was carried out with the DFT:B3LYP/PBE1PBE methods, revealing electronic delocalization effects involving CoS and CN bonds and their neighboring groups. The observed valence configurations for the alpha and beta electrons of the cobalt atom were (4s)0.46(3d)7.69 (B3LYP) and (4s)0.46(3d)7,68 (PBE1PBE), as expected for the planar structure around the Co(II) cation. The calculated infrared and UV-Vis spectra, based on the proposed geometrical structure of the bis(diethyldithiocarbamate)cobalt(II) complex, showed an excellent agreement with the experimental spectra.

THE DIRECT ELECTROCHEMICAL SYNTHESIS OF DIALKYLDITHIOCARBAMATE AND DIETHYLDITHIOPHOSPHATE COMPLEXES OF MAIN GROUP AND TRANSITION METALS

Dialkyldithiocarbamate derivatives (R2NCS2)nM of a number of metals (M=Fe, Co, Ni, Cu, Ag, Zn, Cd, In, Tl) have been synthesised in good yield by electrochemical oxidation of appropriate sacrificial anodes in non-aqueous solutions of either the corresponding tetraalkylthiuran disulphide (R2NCS2)2 (R=Me, Et) or a mixture of carbon disulphide plus the secondary amine R2NH (R=Et, i-Pr; R2NH=piperidine).Similar experiments with solutions of (EtO)2P(S)SH (=HL) gave MLn* derivatives (M=Fe, Co, Ni, Cu, Ag, Au, Zn, Cd, Hg, Ga, In, Tl) while in the presence of HL+1,10-phenanthroline, MLn.phen derivatives were obtained for M=V, Mn, Fe, Co, Zn, and Ga.

Electrochemical reduction and oxidation of cobalt(III) dithiocarbamates

The literature describing the oxidation and reduction of cobalt(III) dithiocarbamate complexes, Co(R2dtc)3, and the chemistry of formally cobalt(II) and cobalt(IV) dithiocarbamate complexes contains substantially conflicting data. An extensive investigation of the electrochemical reduction and oxidation of Co(R2dtc)3 leads to the following conclusions: (i) In CH2Cl2 and for R = cyclohexyl, controlled-potential oxidative electrolysis at platinum electrodes produces a complex that appears to be the elusive cobalt(IV) complex [Co(R2dtc)3]+ (or possibly [Co2(R2dtc)6]2+ or related species). In acetone, electrolysis of the cyclohexyl derivative at platinum electrodes produces the cobalt(III) dimer [Co2(R2dtc)5]+. At mercury electrodes, the oxidation process proceeds via a pathway different from that at platinum electrodes and [Co2(R2dtc)5]+ and mercury dithiocarbamate complexes are obtained as products. (ii) On the electrochemical time scale, oxidation of most Co(R2dtc)3 complexes is chemically reversible in CH2Cl2 but not always in acetone or acetonitrile, implying that [Co(R2dtc)3]+ has a finite stability for many complexes, at least in CH2Cl2. However, with the exception of R = cyclohexyl, noted above, this complex is not obtained from electrolysis experiments. While [Co2(R2dtc)5]+ rather than [Co(R2dtc)3]+ may be isolated from the oxidized solution in CH2Cl2, it is not formed at the electrode surface and results from a series of chemical reactions subsequent to electron transfer. (iii) Electrochemical reduction of Co(R2dtc)3 is extremely complex and depends markedly on the nature of the R group, solvent, and electrode. Formation of [Co(R2dtc)3]- is favored by solvents such as acetone or acetonitrile and is stabilized by adsorption on mercury electrodes. Thus, chemically reversible one-electron reduction steps are observed in some circumstances. By contrast, Co(R2dtc)2 appears to be significantly more stable in CH2Cl2 than [Co(R2dtc)3]-, and chemically irreversible reduction is generally associated with this solvent at platinum electrodes. The nature of further electrochemical reduction steps, which ultimately produce cobalt metal and dissociated ligands, also depends on numerous variables.