1597408-52-0

Basic information

• Product Name: (E)-2-bromo-1-[2-(4,5-dimethoxy-2-nitrostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl]propan-1-one
• Synonyms: (E)-2-bromo-1-[2-(4,5-dimethoxy-2-nitrostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl]propan-1-one
• CAS NO: 1597408-52-0
• Molecular Weight: 599.459
• Mol File: 1597408-52-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-2-bromo-1-[2-(4,5-dimethoxy-2-nitrostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl]propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-bromo-1-[2-(4,5-dimethoxy-2-nitrostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl]propan-1-one(1597408-52-0)
• EPA Substance Registry System: (E)-2-bromo-1-[2-(4,5-dimethoxy-2-nitrostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl]propan-1-one(1597408-52-0)

Safety Data

• Hazardous Substances Data: 1597408-52-0(Hazardous Substances Data)

Upstream product

• 172877-90-6 1-[2-(bromomethyl)-1-(phenylsulfonyl)-1H-indol-3-yl]propan-1-one 
• 172877-89-3 1-[2-methyl-1-(phenylsulfonyl)-1H-indol-3-yl]propan-1-one 
• 80360-21-0 1-(benzenesulfonyl)-2-methyl-1H-indole 
• 4106-18-7 1-(phenylsulfonyl)-1H-benzo[d][1,2,3]triazole 
• 95-20-5 2-methyl-1H-indole 
• 1597408-46-2 (E)-1-[2-(4,5-dimethoxy-2-nitrostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl]propan-1-one 

Downstream Products

• 1597408-61-1 (E)-1-[2-(4,5-dimethoxy-2-nitrostyryl)-1-(phenylsulfonyl)-1H-indol-3-yl]-2-(phenylsulfonyl)propan-1-one 

Relevant articles and documents

Total Synthesis of Calothrixin B and Its Analogs

The total synthesis of calothrixin B and its analogs was achieved starting from 2-methylindole. The synthesis involved an electrocyclization of 2-nitroarylvinyl-3-phenylsulfonylvinylindoles as a key step to give 2-nitroaryl-4-methoxy-3-methylcarbazoles. Oxidation of these compounds followed by reductive cyclization led to N-phenylsulfonylquinocarbazoles. These quinocarbazoles underwent hydrolysis and aerial oxidation in one pot to give the target compounds.